The peptide library
Every entry states its evidence level and approval status up front. Filter by what the research shows, not by what a product page claims.
ACTH 4-10 (Org 2766)
The nerve-acting fragment of ACTH, developed as a drug candidate for nerve damage and cognitive decline, and abandoned.
BDNF (brain-derived neurotrophic factor)
The brain's main growth factor for plasticity: essential, widely measured, and not something a supplement can deliver.
Cerebrolysin
A porcine brain peptide mixture licensed in parts of Eastern Europe and Asia for stroke and dementia, without EMA or FDA approval.
Cortexin
A polypeptide extract of animal brain cortex used in Russia for cognitive complaints, with no Western regulatory review.
Cortistatin
A somatostatin-like brain peptide studied for slow-wave sleep and memory, with rodent data only.
DSIP
Delta sleep-inducing peptide, a naturally occurring peptide studied in the 1980s for sleep and stress. Research largely stalled and human evidence is weak.
Davunetide (NAP)
An eight-amino-acid neuroprotective peptide that reached phase 3 trials for a rare brain disease and failed.
Dihexa
A synaptogenic peptide with striking rodent results and zero human data — one of the least evidenced compounds sold as a nootropic.
Epitalon
A short synthetic peptide derived from the pineal gland, promoted for longevity and melatonin regulation. Its human evidence is anecdotal, not clinical.
GPE (glycyl-prolyl-glutamate)
A three-amino-acid fragment of IGF-1 studied as a neuroprotective agent in Parkinson's and stroke models.
Galanin
A 29-amino-acid brain peptide that dampens cholinergic signalling, studied in memory and Alzheimer's research.
Glatiramer acetate
A synthetic polypeptide that dampens autoimmune attack in relapsing multiple sclerosis.
Intranasal insulin
Ordinary insulin sprayed into the nose to reach the brain, studied for memory and Alzheimer's with mixed results.
N-Acetyl Semax amidate
A chemically modified Semax heptapeptide sold as a research chemical, with no human trials of the modified form.
Neuropeptide Y
One of the brain's most abundant peptides, studied intranasally for stress resilience and memory.
Orexin A (hypocretin-1)
The hypothalamic peptide that keeps the brain awake; studied intranasally for alertness, not available as a drug.
P21
A four-amino-acid fragment of ciliary neurotrophic factor studied in mice for neurogenesis, and nowhere near human trials.
PACAP-38
A 38-amino-acid neuropeptide used to provoke migraine in research; not a treatment for focus or memory.
Pinealon
A Russian 'bioregulator' tripeptide sold for brain and sleep claims, with no Western clinical trials behind it.
Protirelin (TRH)
Synthetic thyrotropin-releasing hormone: an approved diagnostic injection whose brain-related uses failed in trials.
Selank
A synthetic peptide developed in Russia as an anxiolytic, registered there as a medicine. Western trial data are minimal, so claims should be read cautiously.
Semax
A Russian-registered synthetic peptide derived from ACTH, used as a nasal spray for stroke recovery and cognitive disorders. Western evidence is minimal.
VIP (vasoactive intestinal peptide)
A 28-amino-acid neuropeptide involved in circadian rhythm and brain inflammation, with no approved cognitive use.
Ziconotide
A cone-snail peptide that blocks pain-conducting calcium channels, delivered only into the spinal fluid by pump.