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Pick up to three peptides to see how their mechanisms, studied uses and evidence levels differ. Rows where the entries disagree are marked with a blue edge.
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Comparison
TB-500
Healing & repair
Evidence level
Limited evidence
Approval status
Not approved
Mechanism of action
- 1.The parent molecule, thymosin beta-4, binds actin and helps cells change shape and migrate.
- 2.In animal wound models this is associated with faster movement of repair cells into injured tissue.
- 3.It has been reported to support blood-vessel formation and to reduce inflammatory signalling in tissue models.
- 4.Because the fragment is much shorter than the parent protein, how much of that activity it retains is uncertain.
Studied for
- Skin wound closure (animal and ex-vivo models)
- Tendon and muscle repair models
- Corneal and cardiac repair models
- Hair growth (small cosmetic studies of the parent protein, not the fragment)
Reported effects
- Accelerated wound closure in animal models
- Increased cell migration in laboratory studies
- Reduced scar formation in some models
- Human outcome data are essentially absent
Side effects
- Human safety profile not established
- Injection-site reactions reported anecdotally
- Headache and lethargy reported anecdotally
- Unverified purity is a real risk with unregulated products
Research protocol
Research context only — no approved human protocol exists. Animal studies used injected doses in the microgram-per-kilogram range over days to weeks. Online cycle recommendations are not derived from controlled human research.
Research context only
Evidence justification
Animal and laboratory findings exist for the parent protein and the fragment, but controlled human studies are lacking, so claims about human benefit remain unproven.