Side by side

1. 1.Mimics the active region of ciliary neurotrophic factor rather than the whole protein.
2. 2.In mouse models it increased hippocampal neurogenesis and synaptic protein expression.
3. 3.Reported reduction in tau phosphorylation in transgenic mouse models.
4. 4.Its small size is claimed to allow passage across the blood-brain barrier.
5. 5.No defined human receptor pharmacology has been established.

• Transgenic Alzheimer's mouse models
• Hippocampal neurogenesis and memory tests in rodents
• Stroke and neuroprotection models

• Preclinical effects only; nothing established in humans
• Reported memory improvement in mice, not replicated in people
• No pharmacokinetic or safety data in humans

• Unknown in humans
• Potential for unverified identity or purity in research supply
• Inflammatory effects of the parent molecule are theoretical at fragment scale

Research context only - no approved human protocol exists. Published experiments used mice and cell cultures, typically microgram doses given intraperitoneally or directly into the brain, over days to weeks. Nothing about those doses translates into a human schedule.

Research context only